Etoposide (VePesid) interacts with ECHINACEAĮchinacea might decrease how quickly the body breaks down etoposide.Taking echinacea along with these medications might decrease the effects of these medications. Some medications, such as those used after a transplant, decrease the activity of the immune system. Medications that decrease the immune system (Immunosuppressants) interacts with ECHINACEAĮchinacea can increase the activity of the immune system.Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates) interacts with ECHINACEA.This could change the effects and side effects of these medications. Echinacea might change how quickly the liver breaks down these medications. Some medications are changed and broken down by the liver. Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with ECHINACEA.Taking echinacea along with caffeine might increase levels of caffeine and increase the risk of side effects from caffeine, such as jitteriness, headache, and fast heartbeat. Don't take echinacea if you have an auto-immune disorder.Įchinacea might decrease how quickly the body breaks down caffeine. "Auto- immune disorders" such as such as multiple sclerosis (MS), lupus (systemic lupus erythematosus, SLE), rheumatoid arthritis (RA), a skin disorder called pemphigus vulgaris, or others: Echinacea might have an effect on the immune system that could make these conditions worse. It's best to avoid exposure to echinacea if you have this condition. An inherited tendency toward allergies ( atopy): People with this condition are more likely to develop an allergic reaction to echinacea. There is some concern that allergic reactions to echinacea could be more severe in some children. Taking echinacea by mouth seems to be safe in most children ages 2-11 years, but rashes due to an allergic reaction can occur. Children: Echinacea is possibly safe when taken by mouth or applied to the skin for up to 10 days. Breast-feeding: There isn't enough reliable information to know if echinacea is safe to use when breast-feeding. There isn't enough reliable information to know if using echinacea for longer than 7 days is safe. Pregnancy: Echinacea is possibly safe when taken by mouth for up to 7 days when pregnant.
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